GLPwatch

Byetta vs Ozempic

Drug comparison

Last updated 2026-05-28 15:46 UTC

Byetta (exenatide by AstraZeneca) and Ozempic (semaglutide by Novo Nordisk) are both injectable medications for type 2 diabetes, given under the skin. Ozempic is also approved to lower cardiovascular risk and help with chronic kidney disease, while Byetta is only for diabetes. Both require shots, but they use different active ingredients.

AI summary of the sources below.

Byetta Ozempic
Active ingredientexenatidesemaglutide
Manufacturerastrazenecanovo-nordisk
Routesubcutaneous injectionsubcutaneous injection
FDA-approved fortype 2 diabetestype 2 diabetes, cardiovascular risk reduction, chronic kidney disease
Label updated2025-09-022026-01-30

Compare full details on the Byetta and Ozempic pages.