GLPwatch

Byetta vs Wegovy

Drug comparison

Last updated 2026-05-28 15:46 UTC

Byetta (exenatide by AstraZeneca) is a once-daily injection for type 2 diabetes, while Wegovy (semaglutide by Novo Nordisk) is a once-weekly injection approved for long-term weight management in obesity and to lower cardiovascular risk. Both are given as shots under the skin, but Byetta uses exenatide and Wegovy uses semaglutide, with Wegovy also being the same active ingredient as the diabetes drug Ozempic but at a higher dose.

AI summary of the sources below.

Byetta Wegovy
Active ingredientexenatidesemaglutide
Manufacturerastrazenecanovo-nordisk
Routesubcutaneous injectionsubcutaneous injection
FDA-approved fortype 2 diabetesobesity, cardiovascular risk reduction
Label updated2025-09-022026-05-05

Compare full details on the Byetta and Wegovy pages.