GLPwatch

Dulaglutide vs Tirzepatide

Molecule comparison

Last updated 2026-05-28 15:46 UTC

Dulaglutide (brand name Trulicity) is a GLP-1 receptor agonist approved to treat type 2 diabetes and reduce cardiovascular risk. Tirzepatide (brand names Mounjaro and Zepbound) is a dual GLP-1 and GIP receptor agonist approved for type 2 diabetes, obesity, and obstructive sleep apnea. Both are taken by injection, but dulaglutide is given weekly while tirzepatide dosing varies by condition.

AI summary of the sources below.

Dulaglutide Tirzepatide
MechanismGLP-1 receptor agonistGIP and GLP-1 receptor dual agonist
StatusApprovedApproved
Branded productstrulicitymounjaro, zepbound

Compare full details on the Dulaglutide and Tirzepatide pages.