GLPwatch

Exenatide vs Tirzepatide

Molecule comparison

Last updated 2026-05-28 15:46 UTC

Exenatide is a GLP-1 receptor agonist used to treat type 2 diabetes, available as Byetta or Bydureon. Tirzepatide is a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes, obesity, and obstructive sleep apnea, sold as Mounjaro or Zepbound. Exenatide is injected twice daily or weekly, while tirzepatide is taken as a weekly injection.

AI summary of the sources below.

Exenatide Tirzepatide
MechanismGLP-1 receptor agonistGIP and GLP-1 receptor dual agonist
StatusApprovedApproved
Branded productsbyetta, bydureonmounjaro, zepbound

Compare full details on the Exenatide and Tirzepatide pages.