Semaglutide vs Tirzepatide
Molecule comparison
Last updated 2026-05-28 15:46 UTCSemaglutide (brand names Ozempic, Wegovy, Rybelsus) is a GLP-1 receptor agonist approved to treat type 2 diabetes, obesity, chronic kidney disease, and cardiovascular risk reduction. Tirzepatide (brand names Mounjaro, Zepbound) is a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes, obesity, and obstructive sleep apnea. Both are taken as injections, but Semaglutide is also available as a pill (Rybelsus), while Tirzepatide is only available as an injection.
AI summary of the sources below.
| Semaglutide | Tirzepatide | |
|---|---|---|
| Mechanism | GLP-1 receptor agonist | GIP and GLP-1 receptor dual agonist |
| Status | Approved | Approved |
| Branded products | ozempic, wegovy, rybelsus | mounjaro, zepbound |
Compare full details on the Semaglutide and Tirzepatide pages.