GLPwatch
Trulicity vs Wegovy
Drug comparison
Last updated 2026-05-28 15:46 UTCTrulicity (dulaglutide by Eli Lilly) is a once-weekly injection for type 2 diabetes and reducing cardiovascular risk, while Wegovy (semaglutide by Novo Nordisk) is a once-weekly injection approved for obesity and cardiovascular risk reduction. Both are given as shots under the skin, but they contain different active ingredients and are used for different conditions.
AI summary of the sources below.
| Trulicity | Wegovy | |
|---|---|---|
| Active ingredient | dulaglutide | semaglutide |
| Manufacturer | eli-lilly | novo-nordisk |
| Route | subcutaneous injection | subcutaneous injection |
| FDA-approved for | type 2 diabetes, cardiovascular risk reduction | obesity, cardiovascular risk reduction |
| Label updated | 2023-08-05 | 2026-05-05 |