GLPwatch

Wegovy vs Zepbound

Drug comparison

Last updated 2026-05-28 15:46 UTC

Wegovy (semaglutide, made by Novo Nordisk) and Zepbound (tirzepatide, made by Eli Lilly) are both injected under the skin to help with weight management. Wegovy is approved for obesity and reducing cardiovascular risk, while Zepbound is approved for obesity and obstructive sleep apnea.

AI summary of the sources below.

Wegovy Zepbound
Active ingredientsemaglutidetirzepatide
Manufacturernovo-nordiskeli-lilly
Routesubcutaneous injectionsubcutaneous injection
FDA-approved forobesity, cardiovascular risk reductionobesity, obstructive sleep apnea
Label updated2026-05-052026-04-22

Compare full details on the Wegovy and Zepbound pages.