GLPwatch
Fertility ("Ozempic babies")
Investigational / off-label
Last updated 2026-05-28 15:46 UTCThe source discusses semaglutide in the context of pregnancy but does not provide specific information about fertility or the concept of 'Ozempic babies'.
AI summary of the sources below.
Approved GLP-1 drugs (0)
No GLP-1 drug is FDA-approved for fertility ("ozempic babies") in our data. Any research below reflects investigational or off-label study.
Research (50)
- Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model.
- Obesity, Polycystic Ovary Syndrome, and Infertility: A New Avenue for GLP-1 Receptor Agonists.
- Liraglutide increases IVF pregnancy rates in obese PCOS women with poor response to first-line reproductive treatments: a pilot randomized study.
- The benefits of GLP-1 drugs beyond obesity.
- Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence.
- GLP-1 Increases Preovulatory LH Source and the Number of Mature Follicles, As Well As Synchronizing the Onset of Puberty in Female Rats.
- Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial.
- GLP-1 Receptor Agonist Exenatide Attenuates the Detrimental Effects of Obesity on Inflammatory Profile in Testis and Sperm Quality in Mice.
- Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4.
- Glucagon-like peptide-1 receptor agonist use in pregnancy: a review.
- Glucagon-like peptide-1 receptor is expressed in human and rodent testis.
- The impact of tirzepatide and glucagon-like peptide 1 receptor agonists on oral hormonal contraception.
- Pharmacologic Treatment of Obesity in Reproductive Aged Women.
- Potential Roles of Glucagon-Like Peptide 1 Receptor Agonists (GLP-1 RAs) in Nondiabetic Populations.
- Human Sperm Express the Receptor for Glucagon-like Peptide-1 (GLP-1), Which Affects Sperm Function and Metabolism.
- The effects of liraglutide on male fertility: a case report.
- Effect of metformin and exenatide on pregnancy rate and pregnancy outcomes in overweight or obese infertility PCOS women: long-term follow-up of an RCT.
- Semaglutide and pregnancy.
- Pharmacotherapy: GLP-1 analogues and insulin: sound the wedding bells?
- Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review.
- Case Series: Exposure to Glucagon-like Peptide-1 Receptor Agonist in the First Trimester of Pregnancy in Two Siblings.
- Pharmacological and non-pharmacological strategies for obese women with subfertility.
- Semaglutide early intervention attenuated testicular dysfunction by targeting the GLP-1-PPAR-α-Kisspeptin-Steroidogenesis signaling pathway in a testicular ischemia-reperfusion rat model.
- What is known about the use of weight loss medication in women with overweight/obesity on fertility and reproductive health outcomes? A scoping review.
- Effect of Oral Semaglutide on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol in Healthy Postmenopausal Women and Furosemide and Rosuvastatin in Healthy Subjects.
- Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway.
- Modulatory effect of liraglutide on doxorubicin-induced testicular toxicity and behavioral abnormalities in rats: role of testicular-brain axis.
- Glucagon-like peptide-1 control of GnRH secretion in female sheep.
- Liraglutide treatment effects on rat ovarian and uterine tissues.
- Obstetrician-Gynecologists' Strategies for Patient Initiation and Maintenance of Antiobesity Treatment with Glucagon-Like Peptide-1 Receptor Agonists.
Common questions
- Which GLP-1 drugs are FDA-approved for Fertility ("Ozempic babies")?
- No GLP-1 drug is currently FDA-approved for fertility ("ozempic babies"); any use would be off-label or investigational.
- Is there research on GLP-1 drugs for Fertility ("Ozempic babies")?
- GLPwatch tracks 62 research papers on GLP-1 drugs and fertility ("ozempic babies"). This research is investigational and does not imply FDA approval.