GLPwatch
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
J Allergy Clin Immunol · 2018
Last updated 2026-05-28In mice with a respiratory syncytial virus (RSV) infection, activating GLP-1 receptor signaling reduced harmful type 2 immune responses and lung damage. The study used an RSV strain taken from a hospitalized infant with severe lung infection.
AI summary of the abstract below.
| Journal | J Allergy Clin Immunol, 2018 |
|---|---|
| Citations | 47 |
| Relative citation ratio | 1.77 |
| NIH percentile | 70 |
| Molecules | — |
| Conditions studied | Obstructive Sleep Apnea |
Abstract
GLP-1R signaling, an emerging anti-inflammatory therapeutic 59 target, 60 attenuated type 2-associated immunopathology in mice infected with a strain of RSV that was 61 isolated from a hospitalized infant with severe lower respiratory tract infection and bronchiolitis.
Verbatim abstract via PubMed 29678751 ↗