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Tendency of Semaglutide to Induce Gastroparesis: A Case Report.

Cureus · 2024

Last updated 2026-09-01

A patient taking semaglutide, a drug used for type 2 diabetes and weight loss, developed gastroparesis, a condition that slows stomach emptying. The patient already had symptoms like bloating and nausea before starting the drug, which may have worsened with semaglutide. Gastrointestinal side effects, including gastroparesis, can occur with this medication.

AI summary of the abstract below.

JournalCureus, 2024
Citations21
Relative citation ratio4.38
NIH percentile91
Molecules semaglutide

Abstract

Semaglutide, an agonist of the glucagon-like peptide-1 receptor, is frequently used in the treatment of diabetes mellitus type 2, although, lately, weight loss has additionally become a reason for its use. However, if a patient is already experiencing bloating, nausea, abdominal pain, and discomfort in the abdomen, it is not recommended to use it due to concern about aggravating these symptoms. Although it is often well tolerated, there are occasions when it can have several gastrointestinal side effects. Therefore, we report a case of a patient who started taking semaglutide and later developed gastroparoresis.

Verbatim abstract via PubMed 38371020 ↗

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