Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

NCT00318422 · Completed

Last updated 2026-05-28

This clinical trial tested the effect of the medication liraglutide on blood sugar control in adults with type 2 diabetes.

Status Completed The study has finished.

Phase Phase 3 Confirms effectiveness in a large group before approval.

Type Interventional (clinical trial)

Design Randomized, double-blind treatment study

Participants 1,041 people

Who can join Ages 18–80 · all sexes

Timeline Started 2006-05 · est. completion 2007-05

Where 127 sites · Argentina, Australia, Brazil, Bulgaria, Croatia, Czechia, Finland, France, Greece, India, Israel, Italy, Malaysia, Philippines, Poland, Romania, South Africa, South Korea, Spain, Switzerland, Taiwan, Thailand, Turkey (Türkiye)

What this study is testing ClinicalTrials.gov NCT00318422 ↗

Description as written by the study sponsor.

This trial is conducted globally (the United States of America excepted). This trial is designed to show the effect of treatment with liraglutide when added to existing glimepiride therapy and to compare this to both glimepiride monotherapy and to rosiglitazone as add-on therapy to glimepiride.

Treatments tested

liraglutide Drug
rosiglitazone Drug
glimepiride Drug

Main thing measured	HbA1c
Sponsor	Novo Nordisk A/S
Conditions studied	Diabetes, Diabetes Mellitus, Type 2
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT00318422 ↗