The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes

NCT02008682 · Completed

Last updated 2026-05-28

This clinical trial compares the effects of liraglutide and sitagliptin, both taken with metformin, on blood sugar control in adults with type 2 diabetes.

Status Completed The study has finished.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 368 people

Who can join Ages 18–80 · all sexes

Timeline Started 2013-12 · est. completion 2014-11

Where 25 sites · China

What this study is testing ClinicalTrials.gov NCT02008682 ↗

Description as written by the study sponsor.

This trial is conducted in Asia. The aim of this trial is to investigate the efficacy and safety of liraglutide compared to sitagliptin, both as add-on to metformin in Chinese subjects with type 2 diabetes inadequately controlled on metformin monotherapy. Eligible subjects will continue their metformin background treatment during the trial.

Treatments tested

liraglutide Drug

Administered subcutaneously (s.c., under the skin) once daily as add-on to the subject's stable pre-trial metformin dose.
sitagliptin Drug

Administered orally once daily as add-on to the subject's stable pre-trial metformin dose.

Main thing measured	Change From Baseline in Glycosylated Haemoglobin (HbA1c)
Sponsor	Novo Nordisk A/S
Conditions studied	Diabetes, Diabetes Mellitus, Type 2
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT02008682 ↗