Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People

NCT02308254 · Unknown status

Last updated 2026-05-28

This clinical trial tested the effect of the drug lixisenatide on how quickly the stomach empties and on blood pressure drops in adults with type 2 diabetes and in healthy volunteers.

Status Unknown status The sponsor has not confirmed the status recently.

Phase Phase1, Phase2

Type Interventional (clinical trial)

Design Randomized, double-blind treatment study

Participants 30 people Planned (estimated).

Who can join Ages 40–80 · all sexes Healthy volunteers accepted.

Timeline Started 2013-11 · est. completion 2016-04

Where 1 site · Australia

What this study is testing ClinicalTrials.gov NCT02308254 ↗

Description as written by the study sponsor.

The purpose of this study is to determine the effects of the drug lixisenatide on blood sugar levels, stomach emptying, blood pressure and heart rate, release of gut hormones and blood flow in the gut after a glucose drink in both healthy subjects and people with type 2 diabetes. If lixisenatide is shown to be effective, it would encourage ongoing evaluation of its potential use in the management of the falls in blood pressure following a meal in diabetic patients.

Treatments tested

Lixisenatide also known as Lyxumia Drug

Abdominal administration
Placebo also known as Dummy Drug

Abdominal administration

Main thing measured	Blood Pressure
Sponsor	Royal Adelaide Hospital
Conditions studied	Diabetes Mellitus, Gastroparesis
GLP-1 drugs	lixisenatide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT02308254 ↗