Effects of Glucagon-like-Peptide-1 Analogues on Sexuality

NCT05598008 · Completed

Last updated 2026-05-28

This clinical trial tests whether a type of medication called GLP-1 analogues affects sexual desire in adults experiencing changes in libido.

Status Completed The study has finished.

Type Observational

Participants 85 people

Who can join Ages 18–75 · all sexes Healthy volunteers accepted.

Timeline Started 2022-11 · est. completion 2025-10

Where 1 site · Switzerland

What this study is testing ClinicalTrials.gov NCT05598008 ↗

Description as written by the study sponsor.

This study is to investigate the effects of GLP-1 analogues (combined with lifestyle interventions in comparison to lifestyle interventions only) on sexual desire, mood, quality of life, the reproductive axis, retinal vessel diameters, physical fitness (and semen, for men only) in overweight or obese men and women.

Main thing measured	Change in the German short version of the Sexual Desire Inventory (SDI-2) total score to assess sexual functioning
Sponsor	University Hospital, Basel, Switzerland
Conditions studied	Sexual Desire
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT05598008 ↗