MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease

NCT07478653 · Not yet recruiting

Last updated 2026-05-28

This clinical trial is testing whether a dental care program can improve gum health in children who are overweight or obese.

Status Not yet recruiting Approved but enrollment has not started.

Phase Not applicable Not a phased drug trial (e.g. a device or behavioral study).

Type Interventional (clinical trial)

Design Randomized, single-blind prevention study

Participants 50 people Planned (estimated).

Who can join Ages 12–17 · all sexes

Timeline Started 2026-05 · est. completion 2028-07

Where 1 site · United States

What this study is testing ClinicalTrials.gov NCT07478653 ↗

Description as written by the study sponsor.

The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question\[s\] it aims to answer \[is/are\]: if dental cleaning will improve both oral health and metabolic outcomes beyond the effects of semaglutide alone. Participants will receive either dental cleaning and oral hygiene instruction or oral hygiene instruction alone.

Treatments tested

Dental Cleaning and Oral Hygiene Instruction (OHI) Procedure

Participants receive dental cleaning and oral hygiene instruction (OHI) and oral health assessments at baseline (prior to initiating weight-loss medication), 6 months (±2 weeks), and 12 months (±1 month) post-enrollment.
Oral Hygiene Instruction (OHI) Behavioral

Participants will receive standard oral health care, including instructions on how to care for their teeth (OHI). Dental cleaning provided at 12 months.

Main thing measured	Change in gingival index
Sponsor	Oelisoa Andriankaja
Conditions studied	Obesity, Dental Care for Children
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07478653 ↗